For patients

A targeted, oral therapy designed around patients

Zent-001 is an investigational medicine being studied for its potential to give physicians and patients a targeted, non-chemotherapy option — taken as a pill at home, not as an infusion at a clinic.

How it works

Three steps, designed for everyday life

From screening to daily dosing — here's what the journey could look like.

  1. 01

    Biomarker screening

    A tissue sample is tested for Cyclin E1 amplification to see if the therapy may be a match.

  2. 02

    Physician discussion

    If eligible, your care team reviews whether a Zentia clinical trial is the right next step for you.

  3. 03

    Oral, once-daily dosing

    Take a pill at home each day — no infusion visits, with regular check-ins with your study team.

At a glance What sets it apart Targeted mechanism · Biomarker-matched · Oral dosing

Why it's different

Designed to interrupt the cancer's survival plan

Cancer cells multiply quickly and make mistakes. They rely on a checkpoint protein called WEE1 to survive. Zent-001 blocks that checkpoint, pushing cancer cells past a point of no return.

Because it's matched to tumor biology and taken orally, the therapy is designed to be more convenient than infusion-based care — fewer trips, fewer disruptions to daily life.

  • Not a chemotherapy — a targeted kinase inhibitor
  • Oral, once-daily, at-home administration
  • Developed with a companion diagnostic

Important considerations

What to discuss with your care team

Zent-001 is investigational and not approved by any health authority. There are risks with any medicine, including side effects. Your care team can help you weigh whether a clinical trial is right for you.
— Always discuss your options with your oncologist first
Available to discuss

Support for patients

Our patient information team can help you understand eligibility, connect with a participating site, and answer questions about what participation involves.

For physicians

Information for healthcare professionals

Physicians can contact medical affairs for trial details, eligibility criteria and how to refer patients to participating sites.